STUDYING OXIDATIVE STRESS OF LIPIDS DURING EXPERIMENTAL MYOCARDIAL INFARCTION IN RATS
Keywords:
Experimental myocardial infarction, peroxidation, oxidative stress, free radical oxidation, malondialdehydeAbstract
Myocardial infarction is a serious and common disease throughout the world. A method has been developed to simulate myocardial infarction in laboratory animals using minimally invasive approaches such as coronary artery ligation or controlled electrocoagulation.
Comprehensive measures for anesthesiology, microsurgery and resuscitation were introduced, which led to a significant reduction in postoperative mortality in animals from 94.6% to 13.6%. Diagnostic data suggest the possibility of creating a reliable model of myocardial infarction in laboratory animals.
Further improvement and standardization of experimental modeling of myocardial infarction will make it possible to use this model to search for effective treatment methods.
References
Nasab E. M. et al. COVID-19’s immuno-pathology and cardiovascular diseases //Journal of Investigative Medicine. – 2023. – Т. 71. – №. 2. – С. 71-80.
Neves K. B. et al. Exosomes and the cardiovascular system: role in cardiovascular health and disease //The Journal of Physiology. – 2023. – Т. 601. – №. 22. – С. 4923-4936.
Zeng J. et al. Effect of lipid oxidation on quality attributes and control technologies in dried aquatic animal products: A critical review //Critical Reviews in Food Science and Nutrition. – 2023. – С. 1-22.
Whitworth G. B., Watson F. L. Translating Ribosome Affinity Purification (TRAP) and Bioinformatic RNA-Seq Analysis in Post-metamorphic Xenopus laevis //Axon Regeneration: Methods and Protocols. – New York, NY : Springer US, 2023. – С. 279-310.
Acín-Pérez R. et al. Isolation of mitochondria from mouse tissues for functional analysis //Metabolic Reprogramming: Methods and Protocols. – New York, NY : Springer US, 2023. – С. 77-96.
Kenjayevich B. A., Baxriddinovna U. G. Experimental giperxolesterolemiyada nitrergik tizim dinamikasi //Новости образования: исследование в XXI веке. – 2023. – Т. 1. – №. 9. – С. 1452-1458.
Baykulov A. K., Toshboyev F. N., Akhmadov J. Z. biochemical and physiological changes in parasite parameters in the host-parasite relationship //Modern Scientific Research International Scientific Journal. – 2024. – Т. 2. – №. 1. – С. 257-262.
Akhmadov J. Z., Akramov D. K., Baykulov A. K. chemical composition of essential oil lagochilus setulosus //Modern Scientific Research International Scientific Journal. – 2024. – Т. 2. – №. 1. – С. 263-269.
Bayqulov A. K., Raxmonov F. K., Egamberdiyev K. E. Indicators of endogenous intoxication in the model of burn injury in correction with chitosan derivatives //Educational Research in Universal Sciences. – 2022. – Т. 1. – №. 2. – С. 56-63.
Baykulov A. K., Norberdiyev S. S. eksperimental giperxolesterolemiyada qondagi gomosistein miqdori bilan endoteliy disfunksiyasi bog ‘liligi //Educational Research in Universal Sciences. – 2023. – Т. 2. – №. 3. – С. 396-402.
Bayqulov A. K. et al. experimental giperlipoproteinemiyani xitosan hosulalari bilan korreksiyasi //Zamonaviy fan va ta'lim yangiliklari xalqaro ilmiy jurnal. – 2024. – Т. 2. – №. 2. – С. 230-240.
Байкулов А. К., Убайдуллаева Г. Б., Эшбуриева Б. Р. коррекция экспериментальной гиперлипопротеинемии с производными хитозана //World of Scientific news in Science. – 2024. – Т. 2. – №. 2. – С. 937-947.
Советов К. Т., Байкулов А. К. динамика ибс с корркекцией лдг //Modern Scientific Research International Scientific Journal. – 2023. – Т. 1. – №. 9. – С. 47-55.
Байкулов А. К., Юсуфов Р. Ф., Рузиев К. А. Зависимость дисфункции эндотелия с содержанием гомоцистеина в крови при экспериментальной гиперхолестеринемии //образование наука и инновационные идеи в мире. – 2023. – Т. 17. – №. 1. – С. 101-107.
Байкулов А. К. и др. Воспалительный процесс: от стадии изменений в крови до заживления //International Scientific and Practical Conference World science. – ROST, 2017. – Т. 5. – №. 3. – С. 32-36.
Байкулов А. К. и др. Степень эндогенной интоксикации и липопероксидации в динамике термической травмы и лечении производными хитозана //International Scientific and Practical Conference World science. – ROST, 2017. – Т. 5. – №. 3. – С. 28-31.
Mohideen K. et al. Assessment of oxidative stress by the estimation of lipid peroxidation marker Malondialdehyde (MDA) in patients with chronic periodontitis: a systematic review and meta-analysis //International Journal of Dentistry. – 2023. – Т. 2023
Байкулов А. К., Муртазаева Н. К., Тошбоев Ф. Н. ДИНАМИКА ВЛИЯНИЯ ЛАКТАТДЕГИДРОГЕНАЗЫ ПРИ ЭКСПЕРИМЕНТАЛЬНОМ ИНФАРКТЕ МИОКАРДА //World of Scientific news in Science. – 2024. – Т. 2. – №. 3. – С. 244-251.
Байкулов А. К., Убайдуллаева Г. Б., Эшбуриева Б. Р. Коррекция экспериментальной гиперлипопротеинемии с производными хитозана //World of Scientific news in Science. – 2024. – Т. 2. – №. 2. – С. 937-947.
Kenjayevich B. A. et al. EKSPERIMENTAL GIPERHOMOSISTEINEMIYANI OKSIDLOVCHI STRESS HOLATIDA KELTIRIB CHIQARISH //TADQIQOTLAR. UZ. – 2024. – Т. 40. – №. 1. – С. 25-30.
Ermanov R. T., Qarshiev S. M., Baykulov A. K. CHANGES IN THE NITRERGIC SYSTEM DURING EXPERIMENTAL HYPERCHOLESTEROLEMIA //World of Scientific news in Science. – 2024. – Т. 2. – №. 4. – С. 326-339.
Akhmadov J. Z., Akramov D. K., Baykulov A. K. Chemical composition of essential oil lagochilus setulosus //Modern Scientific Research International Scientific Journal. – 2024. – Т. 2. – №. 1. – С. 263-269.
Bayqulov A. K., Raxmonov F. K., Egamberdiyev K. E. Indicators of endogenous intoxication in the model of burn injury in correction with chitosan derivatives //Educational Research in Universal Sciences. – 2022. – Т. 1. – №. 2. – С. 56-63.
Baykulov A. K., Norberdiyev S. S. eksperimental giperxolesterolemiyada qondagi gomosistein miqdori bilan endoteliy disfunksiyasi bog ‘liligi //Educational Research in Universal Sciences. – 2023. – Т. 2. – №. 3 SPECIAL. – С. 396-402.
Советов К. Т., Байкулов А. К. Динамика ИБС с корркекцией ЛДГ //Modern Scientific Research International Scientific Journal. – 2023. – Т. 1. – №. 9. – С. 47-55.
Байкулов А. К., Юсуфов Р. Ф., Рузиев К. А. Зависимость дисфункции эндотелия с содержанием гомоцистеина в крови при экспериментальной гиперхолестеринемии //образование наука и инновационные идеи в мире. – 2023. – Т. 17. – №. 1. – С. 101-107.
Kenjayevich B. A. et al. Changes of basic intermediates in blood in myocardial infarction //Journal of Positive School Psychology. – 2022. – С. 1775-1781.
Байкулов А. К. и др. Показатели системы оксида азота при экспериментальной гиперхолстеринемии //International Scientific and Practical Conference World science. – ROST, 2017. – Т. 4. – №. 12. – С. 5-8.
Kenjayevich B. A. et al. TIOKSIKOLOGIK KIMYODA ATOM-ABSORBSION SPEKTROSKOPIYA USULLARI //Yangi O'zbekiston taraqqiyotida tadqiqotlarni o'rni va rivojlanish omillari. – 2024. – Т. 12. – №. 1. – С. 101-106.
Kenjayevich B. A. et al. VISMUT ELEMENTINING TOKSIKOLOGIK AHAMYATI //Yangi O'zbekiston taraqqiyotida tadqiqotlarni o'rni va rivojlanish omillari. – 2024. – Т. 12. – №. 1. – С. 82-86.
Kenjayevich B. A. et al. YALLIG'LANISHGA QARSHI NOSTEROID DORI VOSITALARI TOKSIKOLOGIK AHAMIYATI //Ta'limning zamonaviy transformatsiyasi. – 2024. – Т. 12. – №. 2. – С. 38-43.
Anvar o’g’li O. A., Kenjayevich B. A. SUD KIMYOSI EKSPERTIZA LABAROTORIYALARDA QÒLLANILADIGAN DASTLABKI EKSPRESS TAXLIL USULLARI //Ta'limning zamonaviy transformatsiyasi. – 2024. – Т. 12. – №. 2. – С. 44-48.
Muzaffar o’g’li A. M., Kenjayevich B. A. DORIVOR ÒSIMLIKLAR BILAN ZAHARLANISH HOLATLARI //Ta'limning zamonaviy transformatsiyasi. – 2024. – Т. 12. – №. 2. – С. 58-61.
Kenjayevich B. A., Nematjon o’g’li T. D., Rashidovna E. B. SOURCES OF ALKALOIDS AND EFFECTS ON THE BODY //TADQIQOTLAR. UZ. – 2024. – Т. 40. – №. 1. – С. 31-35.
